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- Title
Allergen immunotherapy with heat-killed Listeria monocytogenes alleviates peanut and food-induced anaphylaxis in dogs.
- Authors
Frick, O L; Teuber, S S; Buchanan, B B; Morigasaki, S; Umetsu, D T
- Abstract
Heat-killed Listeria monocytogenes (HKL) potently stimulates interferon (IFN)-gamma production in CD4 T-lymphocytes, and when used as adjuvant for immunotherapy, reduces immunoglobulin (Ig)E production and reverses established allergen-induced airway hyperreactivity (AHR) in a murine model of asthma. We asked if such treatment could decrease established peanut-induced anaphylaxis or cow's milk-induced food allergy in highly food-allergic dogs.
- Publication
Allergy, 2005, Vol 60, Issue 2, p243
- ISSN
0105-4538
- Publication type
Journal Article
- DOI
10.1111/j.1398-9995.2004.00711.x