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- Title
Downregulation of TLR-7 receptor in hepatic and non-hepatic patients with lichen planus.
- Authors
El Tawdy, Amira; Rashed, Laila
- Abstract
Lichen planus (LP) is an inflammatory disease of the skin and oral mucosa. The association of LP and chronic hepatitis C virus (HCV) is well established, with variable prevalence rates among different populations. Toll-like receptors (TLRs) are key regulators of both the innate response and the adaptive response. However, TLRs also interact with endogenous ligands released by necrotic cells, and this process can intensify autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus.
- Publication
International journal of dermatology, 2012, Vol 51, Issue 7, p785
- ISSN
1365-4632
- Publication type
Journal Article
- DOI
10.1111/j.1365-4632.2011.04977.x