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- Title
Perforating lichen nitidus.
- Authors
Itami, A; Ando, I; Kukita, A
- Abstract
A 32-year-old man with no particular family history nor past history visited our clinic in September 1992, with papules that he claimed had developed approximately 3 years earlier. No subjective symptoms accompanied then. On examination, numerous, discrete, pinhead-sized or half-ricecorn-sized, flesh-colored papules were observed on the dorsolateral side of his left hand and fingers. No central dimple or scaling were noticed clinically (Fig. 1). Laboratory tests revealed no abnormal findings. The histopathology of the biopsied specimen showed a circumscribed nest of infiltrating cells closely attached to the epidermis (Fig. 2). These infiltrating cells consisted of mononuclear lymphoid cells and histiocytes. The overlying epidermis was stretched and atrophic. A transepithelial perforation channel existed in direct contact with the surface. Amorphous debris containing cell nuclei lay within the channel (Fig. 2). Lymphoid cells were also observed above the keratin layer overlying the channel. At the lateral margin of the infiltrate, rete ridges extended downward in the manner of a claw clutching a ball. In a periodic-acid-Schiff (PAS)-stained section, a basement defect was observed around the channel.
- Publication
International journal of dermatology, 1994, Vol 33, Issue 5, p382
- ISSN
0011-9059
- Publication type
Journal Article
- DOI
10.1111/j.1365-4362.1994.tb01074.x