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- Title
Implementation of a multi-institutional diffuse intrinsic pontine glioma autopsy protocol and characterization of a primary cell culture.
- Authors
Caretti, V; Jansen, M H A; van Vuurden, D G; Lagerweij, T; Bugiani, M; Horsman, I; Wessels, H; van der Valk, P; Cloos, J; Noske, D P; Vandertop, W P; Wesseling, P; Wurdinger, T; Hulleman, E; Kaspers, G J L
- Abstract
Diffuse intrinsic pontine glioma (DIPG) is a fatal paediatric malignancy. Tumour resection is not possible without serious morbidity and biopsies are rarely performed. The resulting lack of primary DIPG material has made preclinical research practically impossible and has hindered the development of new therapies for this disease. The aim of the current study was to address the lack of primary DIPG material and preclinical models by developing a multi-institutional autopsy protocol.
- Publication
Neuropathology and applied neurobiology, 2013, Vol 39, Issue 4, p426
- ISSN
1365-2990
- Publication type
Journal Article
- DOI
10.1111/j.1365-2990.2012.01294.x