We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3.
- Authors
Shioya, M; Obayashi, S; Tabunoki, H; Arima, K; Saito, Y; Ishida, T; Satoh, J
- Abstract
MicroRNAs (miRNAs) are small non-coding RNAs that regulate translational repression of target mRNAs. Accumulating evidence indicates that various miRNAs, expressed in a spatially and temporally controlled that manner in the brain plays a key role in neuronal development. However, at present, the pathological implication of aberrant miRNA expression in neurodegenerative events remains largely unknown. To identify miRNAs closely associated with neurodegeneration, we performed miRNA expression profiling of brain tissues of various neurodegenerative diseases.
- Publication
Neuropathology and applied neurobiology, 2010, Vol 36, Issue 4, p320
- ISSN
1365-2990
- Publication type
Journal Article
- DOI
10.1111/j.1365-2990.2010.01076.x