We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Role of spinal cord glia in the central processing of peripheral pain perception.
- Authors
Bradesi, S
- Abstract
The discovery that glial activation plays a critical role in the modulation of neuronal functions and affects the spinal processing of nociceptive signalling has brought new understanding on the mechanisms underlying central sensitization involved in chronic pain facilitation. Spinal glial activation is now considered an important component in the development and maintenance of allodynia and hyperalgesia in various models of chronic pain, including neuropathic pain and pain associated with peripheral inflammation. In addition, spinal glial activation is also involved in some forms of visceral hyperalgesia.
- Publication
Neurogastroenterology and motility, 2010, Vol 22, Issue 5, p499
- ISSN
1365-2982
- Publication type
Journal Article
- DOI
10.1111/j.1365-2982.2010.01491.x