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Title
Does the ribosome have initiation and elongation modes of translation?
Authors
Tenson, Tanel; Hauryliuk, Vasili
Abstract
RNA polymerases differ functionally and structurally in the initiation phase of transcription, when polymerization of 8-12 nucleotides occurs, from the later phases of transcription. Here we argue that the ribosome also might have different properties when translating the first codons in open reading frames, as compared with the later phases of translation.