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- Title
Frequency of deletion formation decreases exponentially with distance between short direct repeats.
- Authors
Chédin, F; Dervyn, E; Dervyn, R; Ehrlich, S D; Noirot, P
- Abstract
The effect of distance between 18 bp direct repeats on deletion formation has been examined in Bacillus subtilis. The deletion frequency decreased exponentially by more than 1000-fold as the distance increased from 33 to 2313 bp. This decrease occurred in two distinct phases, which may be determined by DNA-duplex flexibility. A similar relationship between deletion formation and distance was observed in a theta-replicating plasmid and in the chromosome, indicating that this relationship might have a general validity.
- Publication
Molecular microbiology, 1994, Vol 12, Issue 4, p561
- ISSN
0950-382X
- Publication type
Journal Article
- DOI
10.1111/j.1365-2958.1994.tb01042.x