We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Biomolecular sensors utilizing waveguide modes excited by evanescent fields.
- Authors
Fujimaki, M; Rockstuhl, C; Wang, X; Awazu, K; Tominaga, J; Ikeda, T; Koganezawa, Y; Ohki, Y
- Abstract
Properties of evanescent-field-coupled waveguide-mode sensors consisting of a multi-layer structure made of a SiO(2) waveguide, a thin metal layer (Au, Cu, W or Ti), and a high refractive index glass substrate illuminated under the Kretschmann configuration have been theoretically and experimentally investigated. In all cases, reflectivity changes attributed to streptavidin combining to biotinyl groups were observed in close spectral vicinity of the waveguide resonances. The sensors with the Au and the Cu layers show superior sensitivity as compared to those with the W and the Ti layers, whereas the W and Ti layers show better thermal and chemical stability. The results indicate that the materials of thin metal layers should be chosen in accordance with the purpose of sensors and/or environment in which the sensors are used.
- Publication
Journal of microscopy, 2008, Vol 229, Issue Pt 2, p320
- ISSN
1365-2818
- Publication type
Journal Article
- DOI
10.1111/j.1365-2818.2008.01907.x