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- Title
A functional variant in the promoter region regulates the C-reactive protein gene and is a potential candidate for increased risk of atrial fibrillation.
- Authors
Chang, S-N; Tsai, C-T; Wu, C-K; Lee, J-K; Lai, L-P; Huang, S-W; Huang, L-Y; Tseng, C-D; Lin, J-L; Chiang, F-T; Hwang, J-J
- Abstract
In a large population-based cohort, the level of C-reactive protein (CRP) in patients at baseline predicts an increased risk of future development of atrial fibrillation (AF). The mechanism of this increased risk is unknown. Furthermore, both the molecular effects of CRP on atrial myocytes and fibroblasts and whether genetic variants in the CRP gene predispose to AF are also unknown.
- Publication
Journal of internal medicine, 2012, Vol 272, Issue 3, p305
- ISSN
1365-2796
- Publication type
Journal Article
- DOI
10.1111/j.1365-2796.2012.02531.x