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- Title
Combined analyses and extended follow-up of two randomized controlled homocysteine-lowering B-vitamin trials.
- Authors
Ebbing, M; Bønaa, K H; Arnesen, E; Ueland, P M; Nordrehaug, J E; Rasmussen, K; Njølstad, I; Nilsen, D W; Refsum, H; Tverdal, A; Vollset, S E; Schirmer, H; Bleie, Ø; Steigen, T; Midttun, Ø; Fredriksen, A; Pedersen, E R; Nygård, O
- Abstract
In the Norwegian Vitamin Trial and the Western Norway B Vitamin Intervention Trial, patients were randomly assigned to homocysteine-lowering B-vitamins or no such treatment. We investigated their effects on cardiovascular outcomes in the trial populations combined, during the trials and during an extended follow-up, and performed exploratory analyses to determine the usefulness of homocysteine as a predictor of cardiovascular outcomes.
- Publication
Journal of internal medicine, 2010, Vol 268, Issue 4, p367
- ISSN
1365-2796
- Publication type
Journal Article
- DOI
10.1111/j.1365-2796.2010.02259.x