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- Title
Endogenous ouabain and cardiomyopathy in dialysis patients.
- Authors
Stella, P; Manunta, P; Mallamaci, F; Melandri, M; Spotti, D; Tripepi, G; Hamlyn, J M; Malatino, L S; Bianchi, G; Zoccali, C
- Abstract
Endogenous ouabain (EO) is markedly raised in patients with chronic renal failure. As high EO induces myocardial cell hypertrophy in vitro and it is associated with left ventricular hypertrophy (LVH) in essential hypertensives and in patients with heart failure we investigated the relationship between plasma EO and LV mass and geometry in 156 end-stage renal disease (ESRD) patients. EO was measured by a specific radioimmunoassay and by mass spectrometry.
- Publication
Journal of internal medicine, 2008, Vol 263, Issue 3, p274
- ISSN
1365-2796
- Publication type
Journal Article
- DOI
10.1111/j.1365-2796.2007.01883.x