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- Title
Prognostic value of plasma soluble P-selectin and von Willebrand factor as indices of platelet activation and endothelial damage/dysfunction in high-risk patients with hypertension: a sub-study of the Anglo-Scandinavian Cardiac Outcomes Trial.
- Authors
Varughese, G I; Patel, J V; Tomson, J; Blann, A D; Hughes, E A; Lip, G Y H
- Abstract
Abnormal levels of prothrombotic markers have been described in hypertension, but no such marker has yet been shown to reliably predict cardiovascular outcomes in hypertension. We hypothesized that raised circulating levels of soluble P-selectin (sP-sel, an index of platelet activation) and/or von Willebrand factor (vWF, an index of endothelial damage/dysfunction) would predict vascular events in patients treated for cardiovascular risk.
- Publication
Journal of internal medicine, 2007, Vol 261, Issue 4, p384
- ISSN
0954-6820
- Publication type
Journal Article
- DOI
10.1111/j.1365-2796.2007.01770.x