We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Cannabis derivatives therapy for a seronegative stiff-person syndrome: a case report.
- Authors
Vicente-Valor, M I; Garcia-Llopis, P; Mejia Andujar, L; Antonino de la Camara, G; García del Busto, N; Lopez Tinoco, M J; Quintana Vergara, B; Peiro Vilaplana, C; Dominguez Moran, J A; Sánchez Alcaraz, A
- Abstract
Stiff-person syndrome (SPS) is an uncommon and disabling disorder characterized by progressive rigidity and episodic painful spasms involving axial and limb musculature. SPS treatment is mostly based on benzodiazepines, baclofen, immunosuppressants and intravenous immunoglobulin. Cannabis derivatives [tetrahydrocannabinol (THC) and cannabidiol (CBD)] are available as an oromucosal spray (Sativex(®)), indicated as add-on treatment, for symptom improvement in patients with moderate to severe spasticity because of multiple sclerosis (MS). Our objective is to report a case of seronegative SPS successfully treated with THC-CBD oromucosal spray.
- Publication
Journal of clinical pharmacy and therapeutics, 2013, Vol 38, Issue 1, p71
- ISSN
1365-2710
- Publication type
Journal Article
- DOI
10.1111/j.1365-2710.2012.01365.x