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- Title
Transcriptionally-active high-risk human papillomavirus is rare in oral cavity and laryngeal/hypopharyngeal squamous cell carcinomas--a tissue microarray study utilizing E6/E7 mRNA in situ hybridization.
- Authors
Lewis, James S, Jr; Ukpo, Odey C; Ma, Xiao-Jun; Flanagan, John J; Luo, Yuling; Thorstad, Wade L; Chernock, Rebecca D
- Abstract
Human papillomavirus is well established in oropharyngeal squamous cell carcinoma as both causative and prognostic, but its significance in non-oropharyngeal tumours is unclear. In particular, the significance of finding viral DNA is not known. We sought to evaluate nonoropharyngeal squamous cell carcinomas for transcriptionally-active human papillomavirus and to compare this with the presence of viral DNA.
- Publication
Histopathology, 2012, Vol 60, Issue 6, p982
- ISSN
1365-2559
- Publication type
Journal Article
- DOI
10.1111/j.1365-2559.2011.04169.x