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- Title
Hypoxia-inducible factor-1alpha is associated with angiogenesis, and expression of bFGF, PDGF-BB, and EGFR in invasive breast cancer.
- Authors
Bos, R; van Diest, P J; de Jong, J S; van der Groep, P; van der Valk, P; van der Wall, E
- Abstract
Hypoxia-inducible factor-1 (HIF-1) is the key transcription factor regulating the cellular response to hypoxia, including angiogenesis. Growth factors play an important role in tumour growth and angiogenesis and some have been shown to be induced by HIF-1 in vitro. This study investigated if angiogenesis or growth factors or their receptors are associated with HIF-1alpha in invasive breast cancer.
- Publication
Histopathology, 2005, Vol 46, Issue 1, p31
- ISSN
0309-0167
- Publication type
Journal Article
- DOI
10.1111/j.1365-2559.2005.02045.x