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- Title
S-phase fraction determined on fine needle aspirates is an independent prognostic factor in breast cancer - a multivariate study of 770 patients.
- Authors
Gazic, B; Pizem, J; Bracko, M; Cufer, T; Borstnar, S; Pohar-Marinsek, Z; Us-Krasovec, M
- Abstract
The prognostic significance of DNA ploidy and the S-phase fraction (SPF) have been extensively studied in breast cancer, but their clinical utility remains controversial. The type of tumour material can substantially influence flow cytometric DNA measurements. Material obtained by fine needle aspiration (FNA) biopsy is very suitable for flow cytometric DNA analysis because it contains a low proportion of non-tumour cells and less debris than tissue samples.
- Publication
Cytopathology : official journal of the British Society for Clinical Cytology, 2008, Vol 19, Issue 5, p294
- ISSN
1365-2303
- Publication type
Journal Article
- DOI
10.1111/j.1365-2303.2007.00528.x