We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Bisphenol A in polycystic ovary syndrome and its association with liver-spleen axis.
- Authors
Tarantino, Giovanni; Valentino, Rossella; Di Somma, Carolina; D'Esposito, Vittoria; Passaretti, Federica; Pizza, Genoveffa; Brancato, Valentina; Orio, Francesco; Formisano, Pietro; Colao, Annamaria; Savastano, Silvia
- Abstract
Bisphenol A, one of the highest-volume chemicals currently available, is known to act as endocrine disruptor and alters several metabolic functions, including inflammatory pathways. Elevated serum levels of bisphenol A have been found in women with polycystic ovary syndrome (PCOS) and a role of low-grade chronic inflammation has been recently reported in the pathogenesis of this syndrome. Increased spleen volume, a reliable and stable index of chronic inflammation, was strictly associated with the severity of hepatic steatosis (HS) in obese subjects, determining the so-called liver-spleen axis.
- Publication
Clinical endocrinology, 2013, Vol 78, Issue 3, p447
- ISSN
1365-2265
- Publication type
Journal Article
- DOI
10.1111/j.1365-2265.2012.04500.x