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- Title
Cortisol secretory parameters in young exercisers in relation to LH secretion and bone parameters.
- Authors
Ackerman, Kathryn E; Patel, Kamal T; Guereca, Gabriela; Pierce, Lisa; Herzog, David B; Misra, Madhusmita
- Abstract
Amenorrhoea and low bone density are common in excessive exercisers, yet endocrine factors that differentiate adolescent amenorrhoeic exercisers (AE) from eumenorrhoeic exercisers (EE) are unclear. We have previously reported that high ghrelin and low leptin predict lower LH secretion in AE. Leptin and ghrelin impact cortisol secretion, and hypercortisolaemia can inhibit LH pulsatility. We hypothesized that higher cortisol secretion in young endurance weight-bearing AE compared with EE and nonexercisers predicts lower LH secretion, lower levels of a bone formation marker and higher levels of a bone resorption marker.
- Publication
Clinical endocrinology, 2013, Vol 78, Issue 1, p114
- ISSN
1365-2265
- Publication type
Journal Article
- DOI
10.1111/j.1365-2265.2012.04458.x