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- Title
The use of thyroid function tests in the diagnosis of hypopituitarism: definition and evaluation of the TSH Index.
- Authors
Jostel, Andreas; Ryder, W David J; Shalet, Stephen M
- Abstract
TSH secretion in hypopituitary patients may be decreased due to TSH deficiency but it also remains under feedback inhibition by free thyroxine (fT4). We propose a TSH index (TSHI), as 'fT4-adjusted TSH', that corrects for any physiological TSH suppression, to provide a true estimate of pituitary thyrotroph function and any pathological pituitary suppression.
- Publication
Clinical endocrinology, 2009, Vol 71, Issue 4, p529
- ISSN
1365-2265
- Publication type
Journal Article
- DOI
10.1111/j.1365-2265.2009.03534.x