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Title
Difference in development of medullary thyroid carcinoma among carriers of RET mutations in codons 790 and 791.
Authors
Frank-Raue, Karin; Machens, Andreas; Scheuba, Christian; Niederle, Bruno; Dralle, Henning; Raue, Friedhelm; German MEN2 Study Group
Abstract
Hereditary medullary thyroid carcinoma (MTC) is caused by germ-line mutations in the RET proto-oncogene. Our study addresses the difference in development of MTC between rare mutations in RET codons 790, 791 and 804.