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- Title
BRAF mutation associated with other genetic events identifies a subset of aggressive papillary thyroid carcinoma.
- Authors
Costa, Angela M; Herrero, Agustín; Fresno, Manuel F; Heymann, Jonas; Alvarez, José Antonio; Cameselle-Teijeiro, Jose; García-Rostán, Ginesa
- Abstract
BRAF(V600E) mutation represents the most common oncogenic event in sporadic papillary thyroid cancer (PTC). There are, however, significant discrepancies regarding the overall frequency, its prevalence in PTC-variants, and its relationship with clinico-pathological parameters of poor outcome. Moreover, the impact of BRAF(V600E) mutants on tumour-related patient's death has not been evaluated.
- Publication
Clinical endocrinology, 2008, Vol 68, Issue 4, p618
- ISSN
1365-2265
- Publication type
Journal Article
- DOI
10.1111/j.1365-2265.2007.03077.x