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- Title
Profound amplification of secretory-burst mass and anomalous regularity of ACTH secretory process in patients with Nelson's syndrome compared with Cushing's disease.
- Authors
van Aken, Maarten O; Pereira, Alberto M; van den Berg, Gerrit; Romijn, Johannes A; Veldhuis, Johannes D; Roelfsema, Ferdinand
- Abstract
As described originally, Nelson's syndrome is characterized by grossly elevated ACTH concentrations, a sellar mass and skin hyperpigmentation emerging in the course of Cushing's disease after bilateral adrenalectomy. No detailed studies have defined whether the mechanisms directing ACTH secretion differ in Nelson's syndrome and untreated Cushing's disease.
- Publication
Clinical endocrinology, 2004, Vol 60, Issue 6, p765
- ISSN
0300-0664
- Publication type
Journal Article
- DOI
10.1111/j.1365-2265.2004.02052.x