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- Title
Vitamin D and respiratory health.
- Authors
Hughes, D A; Norton, R
- Abstract
Vitamin D is now known to be of physiological importance outside of bone health and calcium homeostasis, and there is mounting evidence that it plays a beneficial role in the prevention and/or treatment of a wide range of diseases. In this brief review the known effects of vitamin D on immune function are described in relation to respiratory health. Vitamin D appears capable of inhibiting pulmonary inflammatory responses while enhancing innate defence mechanisms against respiratory pathogens. Population-based studies showing an association between circulating vitamin D levels and lung function provide strong justification for randomized controlled clinical trials of vitamin D supplementation in patients with respiratory diseases to assess both efficacy and optimal dosage.
- Publication
Clinical and experimental immunology, 2009, Vol 158, Issue 1, p20
- ISSN
1365-2249
- Publication type
Journal Article
- DOI
10.1111/j.1365-2249.2009.04001.x