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- Title
Lower airways inflammation in allergic rhinitics: a comparison with asthmatics and normal controls.
- Authors
Brown, J L; Behndig, A F; Sekerel, B E; Pourazar, J; Blomberg, A; Kelly, F J; Sandström, T; Frew, A J; Wilson, S J
- Abstract
Allergic rhinitis (AR) and asthma represent a continuum of atopic disease. AR is believed to pre-dispose an individual to asthma. Compared with asthmatics and normal controls, the inflammatory response in the lower airways of rhinitics is not fully elucidated. To test the hypothesis that the inflammatory response in the airways of subjects with AR is at a level intermediate between that in normal controls and asthmatics, we have characterized bronchial inflammation and cytokine mRNA levels in non-asthmatic allergic rhinitics and compared it with subjects with allergic asthma and with normal controls.
- Publication
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2007, Vol 37, Issue 5, p688
- ISSN
0954-7894
- Publication type
Journal Article
- DOI
10.1111/j.1365-2222.2007.02695.x