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- Title
Two-fold elevation of expression of FoxM1 transcription factor in mouse embryonic fibroblasts enhances cell cycle checkpoint activity by stimulating p21 and Chk1 transcription.
- Authors
Tan, Y; Chen, Y; Yu, L; Zhu, H; Meng, X; Huang, X; Meng, L; Ding, M; Wang, Z; Shan, L
- Abstract
Forkhead Box M1 (FoxM1) transcription factor regulates expression of cell cycle effective genes and is stabilized by checkpoint kinase 2 (Chk2) to stimulate expression of DNA repair enzymes in response to DNA damage. This study intended to test whether FoxM1 is involved in cell cycle checkpoint pathways.
- Publication
Cell proliferation, 2010, Vol 43, Issue 5, p494
- ISSN
1365-2184
- Publication type
Journal Article
- DOI
10.1111/j.1365-2184.2010.00699.x