We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
CXCL10 reduces melanoma proliferation and invasiveness in vitro and in vivo.
- Authors
Antonicelli, F; Lorin, J; Kurdykowski, S; Gangloff, S C; Le Naour, R; Sallenave, J M; Hornebeck, W; Grange, F; Bernard, P
- Abstract
Melanoma is often infiltrated by inflammatory and immune cells that might either maintain chronic inflammation, therefore promoting tumour growth, or mount an antitumour response to control tumour outcome. In this setting, Th1-oriented lymphocyte infiltration is associated with a better outcome in melanoma. Although the interferon-induced protein CXCL10 is expressed by Th1 immune cells, its receptor was also shown to be involved in melanoma progression and metastasis.
- Publication
The British journal of dermatology, 2011, Vol 164, Issue 4, p720
- ISSN
1365-2133
- Publication type
Journal Article
- DOI
10.1111/j.1365-2133.2010.10176.x