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- Title
Redistribution of the nuclear protein IFI16 into the cytoplasm of ultraviolet B-exposed keratinocytes as a mechanism of autoantigen processing.
- Authors
Costa, S; Borgogna, C; Mondini, M; De Andrea, M; Meroni, P L; Berti, E; Gariglio, M; Landolfo, S
- Abstract
The skin has long been recognized as a prominent target tissue in systemic lupus erythematosus (SLE) which plays a crucial role in the initiation and perpetuation of the autoimmune reaction cascade as a consequence of ultraviolet (UV)-induced keratinocyte apoptosis. Antibodies against IFI16 (interferon-inducible protein 16) have been detected in the sera of patients with SLE.
- Publication
The British journal of dermatology, 2011, Vol 164, Issue 2, p282
- ISSN
1365-2133
- Publication type
Journal Article
- DOI
10.1111/j.1365-2133.2010.10097.x