We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Traditional therapies in the management of moderate to severe chronic plaque psoriasis: an assessment of the benefits and risks.
- Authors
Naldi, L; Griffiths, C E M
- Abstract
Psoriasis is a chronic, recurrent disease that affects between 1% and 3% of the population. Patients with moderate to severe disease generally require phototherapy (e.g. narrowband ultraviolet B radiation), photochemotherapy (oral psoralen plus ultraviolet A radiation) or systemic agents (e.g. ciclosporin, methotrexate, oral retinoids, fumaric acid esters) to control their disease adequately. In general, these therapeutic modalities have proven to be highly effective in the treatment of psoriasis. However, potentially serious toxicities can limit their long-term use. Given that there is no standard therapeutic approach for patients with moderate to severe psoriasis, the benefits and risks of phototherapy, photochemotherapy and systemic therapy must be weighed carefully for each patient, and treatment individualized accordingly. This review summarizes the benefits and risks of traditional, nonbiological therapies for moderate to severe chronic plaque psoriasis.
- Publication
The British journal of dermatology, 2005, Vol 152, Issue 4, p597
- ISSN
0007-0963
- Publication type
Journal Article
- DOI
10.1111/j.1365-2133.2005.06563.x