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- Title
New genetic variant that might improve warfarin dose prediction in African Americans.
- Authors
Schelleman, Hedi; Brensinger, Colleen M; Chen, Jinbo; Finkelman, Brian S; Rieder, Mark J; Kimmel, Stephen E
- Abstract
Variants in the CYP2C9 (i.e. *2 and *3) and VKORC1 (i.e. 1173C/T or -1639G/A) genes have been shown to influence warfarin dose requirements. However, these factors seem to explain less of the dose variability in African Americans who have a lower prevalence of the CYP2C9*2 and *3 and VKORC1 1173T alleles.
- Publication
British journal of clinical pharmacology, 2010, Vol 70, Issue 3, p393
- ISSN
1365-2125
- Publication type
Journal Article
- DOI
10.1111/j.1365-2125.2010.03709.x