We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A model-based approach to treatment comparison in acute migraine.
- Authors
Maas, Hugo J; Danhof, Meindert; Della Pasqua, Oscar
- Abstract
Currently, direct comparisons between 5-HT(1B/d) receptor agonists are used to assess differences and similarities in antimigraine response. Such comparisons depend on the selected sampling time and do not allow evaluation of entire response profiles. A thorough evaluation of drug properties requires that the time course of the response be taken into account. In this investigation we show the advantages of a model-based approach to compare the efficacy of two triptans (sumatriptan vs. naratriptan).
- Publication
British journal of clinical pharmacology, 2006, Vol 62, Issue 5, p591
- ISSN
0306-5251
- Publication type
Journal Article
- DOI
10.1111/j.1365-2125.2006.02670.x