We found a matchYour institution may have access to this item. Find your institution then sign in to continue.TitleSafety and patient outcomes with lubiprostone for up to 52 weeks in patients with irritable bowel syndrome with constipation.AuthorsChey, W D; Drossman, D A; Johanson, J F; Scott, C; Panas, R M; Ueno, RAbstractIrritable bowel syndrome with constipation (IBS-C) significantly decreases quality of life and the ability to perform daily living activities.PublicationAlimentary pharmacology & therapeutics, 2012, Vol 35, Issue 5, p587ISSN1365-2036Publication typeJournal ArticleDOI10.1111/j.1365-2036.2011.04983.x