We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Thiopurine methyl-transferase activity and azathioprine metabolite concentrations do not predict clinical outcome in thiopurine-treated inflammatory bowel disease patients.
- Authors
González-Lama, Y; Bermejo, F; López-Sanromán, A; García-Sánchez, V; Esteve, M; Cabriada, J L; McNicholl, A G; Pajares, R; Casellas, F; Merino, O; Carpio, D; Vera, M I; Muñoz, C; Calvo, M; Benito, L M; Bujanda, L; García-Fernández, F J; Ricart, E; Ginard, D; Velasco, M; Carneros, J A; Manceñido, N; Calvo, M; Algaba, A; Froilan, C; Cara, C; Maté, J; Abreu, L; Gisbert, J P; "Grupo Español de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa (GETECCU)"
- Abstract
Low thiopurine-methyl-transferase (TPMT) activity and high 6-thioguanine-nucleotide (6TGN) concentrations have been linked to therapeutic success in inflammatory bowel disease patients treated with thiopurines; however, this has not been implemented in clinical practice.
- Publication
Alimentary pharmacology & therapeutics, 2011, Vol 34, Issue 5, p544
- ISSN
1365-2036
- Publication type
Journal Article
- DOI
10.1111/j.1365-2036.2011.04756.x