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Title
Nicotine enemas for treatment of ulcerative colitis: a study of the pharmacokinetics and adverse events associated with three doses of nicotine.
Authors
Ingram, J R; Routledge, P; Rhodes, J; Marshall, R W; Buss, D C; Evans, B K; Feyerabend, C; Thomas, G A O
Abstract
Transdermal nicotine is of value in active ulcerative colitis but causes adverse events because of systemic absorption. Nicotine enemas may give rise to fewer adverse events.