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- Title
Mitochondrial dysfunction measured in vivo.
- Authors
Marcinek, D J
- Abstract
Mitochondria are responsible for meeting the majority of the energetic demand of most tissues. They also play a major role in regulating cell survival. These dual roles of mitochondria place them at the centre of many pathologies leading to tissue degeneration and disruption of energy balance. The prominent role of mitochondria in ageing and disease has led to a tremendous growth in mitochondrial research at the cellular and molecular level. We describe below a new non-invasive approach to measure mitochondrial function that will bridge the gap between our understanding of mitochondrial function in vitro and that in the intact organism.
- Publication
Acta physiologica Scandinavica, 2004, Vol 182, Issue 4, p343
- ISSN
0001-6772
- Publication type
Journal Article
- DOI
10.1111/j.1365-201X.2004.01372.x