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- Title
Randomized controlled trial comparing the effectiveness and safety of intranasal and intramuscular naloxone for the treatment of suspected heroin overdose.
- Authors
Kerr, Debra; Kelly, Anne-Maree; Dietze, Paul; Jolley, Damien; Barger, Bill
- Abstract
Traditionally, the opiate antagonist naloxone has been administered parenterally; however, intranasal (i.n.) administration has the potential to reduce the risk of needlestick injury. This is important when working with populations known to have a high prevalence of blood-borne viruses. Preliminary research suggests that i.n. administration might be effective, but suboptimal naloxone solutions were used. This study compared the effectiveness of concentrated (2 mg/ml) i.n. naloxone to intramuscular (i.m.) naloxone for suspected opiate overdose.
- Publication
Addiction (Abingdon, England), 2009, Vol 104, Issue 12, p2067
- ISSN
1360-0443
- Publication type
Journal Article
- DOI
10.1111/j.1360-0443.2009.02724.x