We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Pathobiology of CD30<sup>+</sup> cutaneous T-cell lymphomas.
- Authors
Kadin, Marshall E.
- Abstract
CD30+ cutaneous lymphoproliferative disorders include lymphomatoid papulosis (LyP) and anaplastic large cell lymphoma (ALCL). LyP is associated with development of lymphoma in nearly 20% of patients. Herein is reviewed the clonal relationship of LyP to malignant lymphoma, the concept of a common stem cell for LyP and associated lymphomas, and the role of genetic instability in lymphomagenesis. The possible role of the CD30+ cell as a regulatory T-cell is introduced and a model for progression of LyP to ALCL is illustrated.
- Publication
Journal of Cutaneous Pathology, 2006, Vol 33, p10
- ISSN
0303-6987
- Publication type
Academic Journal
- DOI
10.1111/j.0303-6987.2006.00507.x