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- Title
Signaling pathways in Th2 development.
- Authors
Mowen, Kerri A; Glimcher, Laurie H
- Abstract
In order for an immune response to be successful, it must be of the appropriate type and magnitude. Intracellular residing pathogens require a cell-mediated immune response, whereas extracellular pathogens evoke a humoral immune response. T-helper (Th) cells orchestrate the immune response and are divided into two subsets, Th1 and Th2 cells. Here, we discuss the mechanisms of Th2 development with a focus on signal transduction pathways that influence Th2 differentiation.
- Publication
Immunological reviews, 2004, Vol 202, p203
- ISSN
0105-2896
- Publication type
Journal Article
- DOI
10.1111/j.0105-2896.2004.00209.x