Title

Prenatal Skin Cell Atlas reveals macrophages' role beyond immunity.

Authors

Pattaroni, Céline

Abstract

In this article, we discuss a recently published study by Gopee et al., who have unveiled a surprising role for macrophages in human prenatal skin development, extending far beyond their traditional immune function. By constructing a comprehensive multi‐omics single‐cell atlas of human prenatal skin, they demonstrate that innate immune cells play a key role in hair follicle formation, scarless wound healing and neurovascular development.

Subjects

FETAL development; HAIR follicles; NATURAL immunity; MACROPHAGES; IMMUNITY; WOUND healing

Publication

Immunology & Cell Biology, 2025, Vol 103, Issue 1, p6

ISSN

0818-9641

Publication type

Academic Journal

DOI

10.1111/imcb.12837