We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Identification of KIT activating mutations in paediatric solitary mastocytoma.
- Authors
Ma, Deqin; Stence, Aaron A; Bossler, Aaron B; Hackman, Jason R; Bellizzi, Andrew M
- Abstract
Mastocytosis is an abnormal mast cell proliferation involving one or more organs, in particular the skin and bone marrow. In children, disease is usually limited to the skin, with three distinct clinical presentations: urticaria pigmentosa, diffuse cutaneous mastocytosis and solitary mastocytoma. Although the KIT D816V mutation is typically found in adult-onset mastocytosis, it is less commonly seen in childhood-onset mastocytosis, and the frequency of KIT mutations in paediatric solitary mastocytoma is poorly documented.
- Publication
Histopathology, 2014, Vol 64, Issue 2, p218
- ISSN
1365-2559
- Publication type
Journal Article
- DOI
10.1111/his.12212