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- Title
Expression of the tumour-suppressor maspin in temporal bone carcinoma.
- Authors
Marioni, Gino; Zanoletti, Elisabetta; Stritoni, Paola; Lionello, Marco; Giacomelli, Luciano; Gianatti, Andrea; Cattaneo, Laura; Blandamura, Stella; Mazzoni, Antonio; Martini, Alessandro
- Abstract
Although it accounts for fewer than 0.2% of all head and neck tumours, temporal bone squamous cell carcinoma (SCC) is an aggressive malignancy with a poor prognosis in advanced cases. Novel therapeutic strategies should be developed focusing on specific targeted therapies. Maspin is a serpin showing tumour-suppressing activity which has therapeutic potential. The present study is the first to investigate maspin expression in temporal bone SCCs, using a series of 29 cases.
- Publication
Histopathology, 2013, Vol 63, Issue 2, p242
- ISSN
1365-2559
- Publication type
Journal Article
- DOI
10.1111/his.12151