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- Title
Approach towards developing a novel procedure to selectively quantify topically applied substances in the hair follicles of the model tissue porcine ear skin.
- Authors
Knorr, Fanny; Patzelt, Alexa; Richter, Heike; Schanzer, Sabine; Sterry, Wolfram; Lademann, Juergen
- Abstract
Hair follicles represent reservoirs for localized drug therapy and transport pathways for systemic drug delivery. This study describes an approach towards developing a novel procedure for quantifying topically applied substances located in the hair follicles of porcine ear skin, a model for human in vivo skin, using a fluorescent dye. Approximately 5% of the topically applied dye was recovered from the hair follicles, which is in accordance with a previous study.
- Publication
Experimental dermatology, 2013, Vol 22, Issue 6, p417
- ISSN
1600-0625
- Publication type
Research
- DOI
10.1111/exd.12113