Title

Identification and characterization of cardiac sarcoidosis with positron emission tomography.

Authors

Schindler, Thomas Hellmuth; Anderson, Adam; El Ghannudi, Soraya; Imperiale, Alessio

Abstract

(2B) Reangulated 99mTc-tetrofosmin single photon emission computed tomography (SPECT/CT) rest perfusion images (short, vertical and horizontal axis) signifies a large perfusion deficit involving the inferolateral wall with mild extension inferiorly and apically associated with corresponding abnormal 18F-FDG uptake on PET/CT images. Cardiac sarcoidosis activity is commonly seen in the basal segments of the septum or lateral wall but may affect also any other myocardial segments like in inflammatory cardiomyopathy,9,10 while normal perfusion and no abnormal SP 18 sp F-FDG reliably rules out cardiac sarcoid disease. Notably, reduced regional perfusion correlating with an abnormal SP 18 sp F-FDG uptake indicates a "mismatch" between a focal decrease in myocardial perfusion and abnormal SP 18 sp F-FDG uptake (inflammation) (Figure 2).

Subjects

SARCOIDOSIS; POSITRON emission tomography; LOW-molecular-weight heparin; MYOCARDIAL perfusion imaging; ARRHYTHMIA

Publication

European Journal of Clinical Investigation, 2022, Vol 52, Issue 2, p1

ISSN

0014-2972

Publication type

Academic Journal

DOI

10.1111/eci.13722