Title

Aplastic anaemia in pregnancy – a single centre, North American series.

Authors

McGowan, Kelly E.; Malinowski, Ann K.; Schuh, Andre C.; Whittle, Wendy; Shehata, Nadine

Abstract

Summary: Aplastic anaemia (AA) is infrequently observed in pregnancy. We describe 19 pregnancies in 9 women at a tertiary care centre over a period of 30 years. Spontaneous resolution of AA did not occur postpartum in the five pregnancies where AA was first diagnosed in pregnancy. In the remaining pregnancies, although haematological indices declined and transfusion support was needed in 35% of pregnancies, relapses were not observed. There were no deaths, but complications occurred in 79% of pregnancies. Preterm delivery and postpartum haemorrhage were observed in 21% and 26% of pregnancies, respectively.

Publication

British Journal of Haematology, 2019, Vol 184, Issue 3, p436

ISSN

0007-1048

Publication type

Academic Journal

DOI

10.1111/bjh.15654