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- Title
Bacterial modulation of human fetal membrane Toll-like receptor expression.
- Authors
Abrahams, Vikki M; Potter, Julie A; Bhat, Geeta; Peltier, Morgan R; Saade, George; Menon, Ramkumar
- Abstract
Preterm premature rupture of fetal membranes (pPROM) occurs in 30-40% of spontaneous preterm births (PTB) and is associated with intra-amniotic infection and inflammation. The membranes may sense and respond to microbes via Toll-like receptors (TLRs); however, little is known about their expression and regulation in this tissue. The objective of this study was to evaluate the expression of TLRs 1-10 in fetal membranes after exposure to pathogens associated with intra-amniotic infection and PTB.
- Publication
American journal of reproductive immunology (New York, N.Y. : 1989), 2013, Vol 69, Issue 1, p33
- ISSN
1600-0897
- Publication type
Journal Article
- DOI
10.1111/aji.12016