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- Title
Comparison between neoadjuvant and adjuvant gemcitabine plus cisplatin chemotherapy for muscle-invasive bladder cancer.
- Authors
Matsubara, Nobuaki; Mukai, Hirofumi; Naito, Yoichi; Nezu, Masahiko; Itoh, Kuniaki
- Abstract
Radical cystectomy plus platinum-based perioperative chemotherapy is a standard treatment for patients with clinically localized muscle-invasive bladder cancer. The standard perioperative chemotherapy is methotrexate, vinblastine, doxorubicin and cisplatin (MVAC). However, no prospective randomized trial has been published that compares neoadjuvant and adjuvant chemotherapy for bladder cancer. Moreover, the efficacy of perioperative chemotherapy with gemcitabine plus cisplatin (GC) has not been clarified. In this study we have compared the clinical outcomes between neoadjuvant and adjuvant chemotherapy in patients receiving GC.
- Publication
Asia-Pacific journal of clinical oncology, 2013, Vol 9, Issue 4, p310
- ISSN
1743-7563
- Publication type
Journal Article
- DOI
10.1111/ajco.12017