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- Title
Genome-wide association study of osteochondrosis in the tarsocrural joint of Dutch Warmblood horses identifies susceptibility loci on chromosomes 3 and 10.
- Authors
Orr, N; Hill, E W; Gu, J; Govindarajan, P; Conroy, J; van Grevenhof, E M; Ducro, B J; van Arendonk, J A M; Knaap, J H; van Weeren, P R; Machugh, D E; Ennis, S; Brama, P A J
- Abstract
Equine osteochondrosis is a developmental joint disease that is a significant source of morbidity affecting multiple breeds of horse. The genetic variants underlying osteochondrosis susceptibility have not been established. Here, we describe the results of a genome-wide association study of osteochondrosis using 90 cases and 111 controls from a population of Dutch Warmblood horses. We report putative associations between osteochondrosis and loci on chromosome 3 (BIEC2-808543; P = 5.03 × 10(-7) ) and chromosome 10 (BIEC2-121323; P = 2.62 × 10(-7) ).
- Publication
Animal genetics, 2013, Vol 44, Issue 4, p408
- ISSN
1365-2052
- Publication type
Journal Article
- DOI
10.1111/age.12016