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- Title
Cortisol levels are influenced by sedation in the acute phase after subarachnoid haemorrhage.
- Authors
Lindgren, C; Dahlqvist, P; Lindvall, P; Nilsson, L; Koskinen, L-O; Naredi, S
- Abstract
Subarachnoid haemorrhage (SAH) is a life-threatening condition that may be aggravated by acute pituitary damage and cortisol insufficiency. Robust diagnostic criteria for critical illness-related corticosteroid insufficiency (CIRCI) are lacking. The aim of this study was to assess the frequency of CIRCI in the acute phase (0-240 h) after SAH and to evaluate associations between cortisol levels and clinical parameters (sedation, circulatory failure, gender, age, severity of disease, treatment). CIRCI was defined as a single morning serum cortisol (mSC) < 200 nmol/L. The lower limit for calculated free cortisol (cFC) was set at < 22 nmol/L, and for saliva cortisol at < 7.7 nmol/L.
- Publication
Acta anaesthesiologica Scandinavica, 2013, Vol 57, Issue 4, p452
- ISSN
1399-6576
- Publication type
Journal Article
- DOI
10.1111/aas.12014