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- Title
Inhibition of axon reflex vasodilatation by topically applied capsaicin.
- Authors
Bernstein, J E; Swift, R M; Soltani, K; Lorincz, A L
- Abstract
Topical application of capsaicin to human skin produced an initial burning erythematous reaction which diminished over 24 hr leaving the skin unresponsive to histamine-induced axon reflex vasodilatation without altering sensitivity to pain, touch and temperature. Depletion of substance P from local sensory nerve terminals is suggested as a possible explanation for this capsaicin effect.
- Publication
The Journal of investigative dermatology, 1981, Vol 76, Issue 5, p394
- ISSN
0022-202X
- Publication type
Journal Article
- DOI
10.1111/1523-1747.ep12520912