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- Title
Action spectrum for phototherapy of psoriasis.
- Authors
Parrish, J A; Jaenicke, K F
- Abstract
Using a monochromator the action spectrum for ultraviolet phototherapy of psoriasis was determined for radiation between 254 and 313 nm and compared to the action spectrum for erythema of uninvolved adjacent skin. Daily exposures of different doses of 254, 280, 290, 296, 300, 304 and 313 nm radiation were observed. Wavelengths of 254, 280, 290 nm were erythemogenic but not therapeutic even at 10 to 50 times the minimal erythema dose. At the other wavelengths studied, the 2 action spectra were similar. In general, fixed daily doses cleared at lower cumulative dose than did incrementally increased daily doses. The small number of suberythemogenic exposure doses required suggests that monochromatic radiation may have advantages over broadband sources.
- Publication
The Journal of investigative dermatology, 1981, Vol 76, Issue 5, p359
- ISSN
0022-202X
- Publication type
Journal Article
- DOI
10.1111/1523-1747.ep12520022